YFV infection exhibits a broad spectrum of clinical presentations. Some individuals experienced a self-limited or mild febrile illness and a significant portion progress to severe manifestation, including complication of severe hemorrhage and liver diseases.
Among those who developed several diseases 30-60% dies.
Yellow fever virus is estimated to cause 200,000 cases of disease and 30,000 deaths each year, with 90% occurring in Africa.
40 countries are considered endemic and at high-risk for YF outbreaks.
The vaccine from Sanofi Pauster (YF-VAX) is available, the vaccination coverage remains inadequate in endemic areas, especially during outbreaks.
There is any antiviral available to support on the treatment.